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In case you miss out on a dose, take it once you recall. If it is close to the time of another dose, skip the skipped dose. Just take your future dose for the typical time. Will not double the dose to catch up.Additionally, discontinuation of concomitantly employed cytochrome P450 3A4, 2B6, 2C19, or 2C9 inducers can also cause an increase in methad